Research of Ocular Hemodynamics by Optical Coherence Tomography and Transpalpebral Rheoophthalmography Methods

Abstract

The main task of this work was to find the connection between ocular hemodynamic parameters and the lamina cribrosa parameters of the eyes with primary open angle glaucoma (POAG). The study was conducted on 51 eyes of 34 subjects, including 11 eyes without ophthalmopathology (control group, average age 49.4 ± 17.5 years), 15 eyes of patients with the 1st (initial) stage of POAG (group 1, average age 67.0 ± 7.6 years), 15 eyes with II (developed) stage of glaucoma (group 2, average age 75.4 ± 6.1 years) and 10 eyes with III (advanced) disease stage (group 3, average age 70.3 ± 5.4 years). The aim of this work was the study of the parameters analyzed in the diagnosis of POAG, which were obtained in two complementary ways: optical coherence tomography (OCT) with angiography function and transpalpebral rheoophthalmography (TP ROG). A pronounced positive correlation established between the sclera lamina cribrosa in OCT and rheographic parameters indicates that the TP ROG reflects, among other things, the hemodynamics in medium and large choroidal vessels passing through the retinal nerve fiber layer. The results indicate the promise of further research in this area to develop new effective individual criteria for the early detection and monitoring of POAG.