Helindicine (1), a new pyrrolizidine alkaloid with unusual structural features, together with the known lycopsamine (2), were isolated from the roots of Heliotropium indicum (Boraginaceae). The structures were established by a combination of 1D and 2D NMR methods (COSY, HMQC, HMBC, and NOESY) and HREIMS. This is the first report of a lactone pyrrolizidine alkaloid in the genus Heliotropium. Compounds 1 and 2 were assayed for antioxidant activity and showed moderate activity. ©2005 Sociedade Brasileira de Química.
CITATION STYLE
Souza, J. S. N., Machado, L. L., Pessoa, O. D. L., Braz-Filho, R., Overk, C. R., Yao, P., … Lemos, T. L. G. (2005). Pyrrolizidine alkaloids from Heliotropium indicum. Journal of the Brazilian Chemical Society, 16(6 B), 1410–1414. https://doi.org/10.1590/S0103-50532005000800019
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