Chromatin structure at active genes

Abstract

For gene switching, chromatin must be manipulated, a process initiating at key cis-controlling elements, labelled operationally as DNaseI hypersensitive sites (DHS). This minireview series expands on how the remodelling of chromatin structure comes about and the consequences for gene activation and repression © Journal compilation © 2011 FEBS. No claim to original UK government works.