Serum Amylin Indicates Hypertriglyceridemia in Pre-diabetics

Abstract

Background: Hypertriglyceridemia is associated with increased insulin secretion and the incidence of Type 2 Diabetes. Studies in rodents and obese children have proposed a relationship between hypertriglyceridemia and elevated plasma amylin levels. However, there are limited data regarding serum amylin and triglyceride levels in adult human subjects with impaired glucose tolerance. In this study, we evaluated the association between serum triglycerides with circulating amylin levels in adult subjects with and without impaired glucose tolerance.