Taxumairols X - Z, new taxoids from Taiwanese Taxus mairei

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Abstract

In addition to 19-dydroxybaccatin III, 1β-hydroxy-5α- deacetylbaccatin I, taxayuntin G and 13-O-deacetyltaxumairol Z (4), three new taxane diterpenoids, taxumairols X (1), Y (2), Z (3) have been isolated from extracts of the Formosan Taxus mairei (LEMEE & LEVL.) S. Y. HU. Compounds 1 - 2 belong to the 11(15→1)-abeo-taxane system, having a tetrahydrofuran ring at C-2, C-3, C-4 and C-20. The new compound 3 and 4, which was misidentified previously are derivatives of 11(15→1)-abeo-taxane with an intact oxirane system. The structures of compounds 1 - 4 were elucidated on the basis of extensive two dimensional (2D)-NMR analysis. © 2002 Pharmaceutical Society of Japan.

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APA

Shen, Y. C., Chang, Y. T., Wang, S. S., Lin, Y. C., & Chen, C. Y. (2002). Taxumairols X - Z, new taxoids from Taiwanese Taxus mairei. Chemical and Pharmaceutical Bulletin, 50(12), 1561–1565. https://doi.org/10.1248/cpb.50.1561

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