Temazepam or midazolam for night sedation. A double‐blind study

Abstract

The effects of oral temazepam (20 mg), oral midazolam (15 mg) and a placebo were compared for night sedation on the evening prior to surgery in a double‐blind study. Patients in the placebo group had significantly worse sleep than those in the temazepam (p = 0.004) or midazolam groups (p = 0.04). There was no significant difference between the two drug groups, nor between the residual effects of the three treatments. Temazepam appears to be somewhat more effective than the ultrashort‐acting midazolam in pre‐operative transient insomnia. Copyright © 1989, Wiley Blackwell. All rights reserved