Subfoveal choroidal thickness and retinal nerve fiber layer alterations in chronic heart failure patients

Abstract

Purpose: To comparatively evaluate the subfoveal choroidal thickness and the peripapillary retinal nerve fiber layer thickness in patients with chronic heart failure relative to control subjects. Methods: A total of 72 chronic heart failure patients and 40 healthy control subjects were enrolled in this were categorized into 2 groups: group 1: patients with 30-50% left ventricle ejection fraction and group 2: corresponding fraction value of <30%. The subfoveal choroidal thickness and the peripapillary retinal nerve fiber layer thickness were measured by spectral domain-optical tomography. Results: The mean subfoveal choroidal thickness was 250.24 ± 68.34 μm in group 1 and 216.72 ± 2, while it was 273.64 ± 77.68 μm in the The differences among the 3 groups were statistically peripapillary retinal nerve fiber layer thicknesses were 100.34 ± 8.24, 95.44 ± 6.67, and 102.34 in the peripapillary retinal nerve fiber layer thicknesses between group 1 and control group, but it was significantly lower in group Conclusion: Our study thus revealed that the subfoveal was lower in patients belonging to both the heart failure groups in comparison to those in the control group. However, the alteration in the peripapillary retinal nerve fiber layer thickness was noted in only patients with <30% left the clinical practice, reductions in these values are correlated with decreased left ventricle ejection chorioretinal diseases and the patients with chronic heart failures.