In this study, new derivatives of pyrazole, isoxazole, pyrazolylthiazole, and azolopyrimidine having a thiophene ring were synthesized under microwave irradiation. Their pharmacological activity toward bacteria and fungi inhibition was screened and compared to the references Chloramphenicol and Trimethoprim/sulphamethoxazole. The antimicrobial results of the investigated compounds revealed promising results and some derivatives have activities similar to the references used.
CITATION STYLE
Gomha, S. M., Farghaly, T. A., Mabkhot, Y. N., Zayed, M. E. M., & Mohamed, A. M. G. (2017). Microwave-assisted synthesis of some novel azoles and azolopyrimidines as antimicrobial agents. Molecules, 22(3). https://doi.org/10.3390/molecules22030346
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