BALO : a “mini lung” model to study cell–cell interactions

Abstract

Stem cell-derived organoid models have emerged as a valuable tool for studying organogenesis, cell-to-cell stromal communication and disease. In this issue, Vazquez-Armendariz et al (2020) report a murine lung stem cell-based bronchioalveolar organoid system and provide insights into the effect of co-culturing with immune and mesenchymal cells.