Simple fractal method of assessment of histological images for application in medical diagnostics

Abstract

We propose new method of assessment of histological images for medical diagnostics. 2-D image is preprocessed to form 1-D landscapes or 1-D signature of the image contour and then their complexity is analyzed using Higuchi's fractal dimension method. The method may have broad medical application, from choosing implant materials to differentiation between benign masses and malignant breast tumors. © 2010 Klonowski et al; licensee BioMed Central Ltd.