Crystal structure of 4-benzylcarbamoyl-1-methylpyridin-1-ium iodide: An efficient multimodal antiviral drug Drebushchak T. N.

Abstract

In the title compound, [MeC5H4NCONHCH2C6H5]I or C14H15N2O+·I-, a cation and an anion form an ionic pair linked by a strong N-H·I hydrogen bond. In the crystal, ionic pairs linked by weak C-H·I hydrogen bonds form infinite ribbons along the crystallographic a axis. Polymorphism screening varying crystallization solvents (water, acetone 90%-water, ethanol 90%-water, 2-propanol 90%-water, DMF, DMSO, methanol, acetonitrile) and conditions (solution temperature, heating and cooling protocols) did not reveal any other polymorphs than the one reported in this work.