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Purine and Pyrimidine-Based Analogs and Suicide Gene Therapy

  • Gojkovic Z
  • Karlsson A
Humana Press, (2007), 403-439
DOI: 10.1007/978-1-59745-148-2_16
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Abstract

Nucleobase and nucleoside analogs are widely used chemotherapeutic agents in the treatment of cancer and viral diseases. These compounds inhibit or disrupt DNA synthesis, and as tumor cells usually divide more rapidly than normal cells, there is a narrow therapeutic...

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Gojkovic, Z., & Karlsson, A. (2007). Purine and Pyrimidine-Based Analogs and Suicide Gene Therapy. In Deoxynucleoside Analogs In Cancer Therapy (pp. 403–439). Humana Press. https://doi.org/10.1007/978-1-59745-148-2_16

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