Prevalence of urinary tract infections and their antibiotic sensitivity in tertiary care hospital Lahore

Abstract

This cross sectional study was conducted to determine the prevalence of UTI among population visiting Jinnah Hospital Lahore to identify microorganisms responsible for UTI to explore sensitivity patterns of identified microorganisms to certain antibiotics used in the cure of UTI. This study included 378 samples of all age groups. In this study we utilized two main approaches, questionnaire and urine testing (urinalysis and urine culture). 151 samples showed no growth on culture plates for taking antibiotics at the time of collection of samples. The positive samples for pathogenic microorganisms were 197. Out of those positive cases gram negative bacteria were found responsible for 81.92% of UTIs in comparison to gram positive bacteria which were 18.08%. Escherichia coli were the most predominant uro-pathogen with 34% followed by Klebsiella spp. 18.78% and Staphylococcus spp. 12.67%. The prevalence of Candida spp. 20.30% was also very high in males and females. Urine culture is an important diagnostic tool to confirm UTI. Rules must be put on the consumption of antibiotics to limit their abuse and misuse. Physicians are advised to use antibiotics like sulzone, nitrofuration, tazocin and imipenum for gram negative bacteria and tetracycline against gram positive bacteria, these antibiotics showed a low resistance rate in that study over commonly used antibiotics.