The relieving effects of brainpower advanced, a dietary supplement, in older adults with subjective memory complaints: A randomized, double-blind, placebo-controlled trial

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Abstract

Subjective memory complaints (SMCs) are common in older adults that can often predict further cognitive impairment. No proven effective agents are available for SMCs. The effect of BrainPower Advanced, a dietary supplement consisting of herbal extracts, nutrients, and vitamins, was evaluated in 98 volunteers with SMCs, averaging 67 years of age (47-88), in a randomized, double-blind, placebo-controlled trial. Subjective hypomnesis/memory loss (SML) and attention/concentration deficits (SAD) were evaluated before and after 12-week supplementation of BrainPower Advanced capsules (n=47) or placebo (n=51), using a 5-point memory questionnaire (1 = no/slight, 5 = severe). Objective memory function was evaluated using 3 subtests of visual/audio memory, abstraction, and memory recall that gave a combined total score. The BrainPower Advanced group had more cases of severe SML (severity 3) (44/47) and severe SAD (43/47) than the placebo group (39/51 and 37/51, < 0.05, < 0.05, resp.) before the treatment. BrainPower Advanced intervention, however, improved a greater proportion of the severe SML (29.5%)(13/44) (P<0.01) and SAD (34.9%)(15/43)(P<0.01) than placebo (5.1% (2/39) and 13.5% (5/37), resp.). Thus, 3-month BrainPower Advanced supplementation appears to be beneficial to older adults with SMCs.

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Zhu, J., Shi, R., Chen, S., Dai, L., Shen, T., Feng, Y., … Xing, G. (2016). The relieving effects of brainpower advanced, a dietary supplement, in older adults with subjective memory complaints: A randomized, double-blind, placebo-controlled trial. Evidence-Based Complementary and Alternative Medicine, 2016. https://doi.org/10.1155/2016/7898093

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