Abstract
This case discusses the pharmacokinetic interaction between simvastatin and ketoconazole resulting in rhabdomyolysis. Simvastatin is a cytochrome P450 3A4 substrate and ketoconazole is a 3A4 inhibitor.
Cite
CITATION STYLE
APA
Mitchell, B. (2015). The statin trilogy (II): Tripped and fell at the train “Statin”: Fatal Forty DDI: Simavastatin, itraconazole, CYP3A4. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 623–625). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_138
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