Multimodal Hemodynamic Neuromonitoring - Quality and Consequences for Therapy of Severely Head Injured Patients

Abstract

Fifty-five head injured patients (GCS <15mm Hg) in up to 50% frequency during the first days after trauma and a second peak after day 6 to 8 according to evidence of CPP insults. Knowledge of baseline p(ti)O2 and CO2 - reactivity allowed minimizing risk of ischemia by induced hyperventilation and improvement on cerebral microcirculation after mannitol administration could be individually recognized.