Probiotics to counteract biofilm-associated infections

Abstract

Eradication of pathogenic microorganisms without disturbing useful microenvironment is the primary goal in the treatment of biofilm-based infections. Although conventional treatment delivering antibody or or antibody-like molecules suppress the infection but fails to accomplish complete removal of infection. Novel treatments using probiotics proved to be more beneficial in the disruption of biofilm-related infections and become an emerging field of investigation. This novel treatment is still in preliminary stage and further research should be focused on viability, functionality and efficacy of the probiotic strains. To know the complete mechanism through which it exerts its effect, detailed molecular level study is also needed. Further studies on probiotics will fill the gaps in the current information and prove its potential in removing biofilm-associated infections.