Applied Effectiveness of Platelet Rich Plasma on Second-degree Facial Burn Healing in Comparison to Conventional facial burn care

Abstract

Keywords: Platelet-rich plasma, second-degree burn, facial burn, wound healing. Background: The standard treatment of partial-thickness facial burns has a slow healing time and unsatisfactory outcome. Applying platelet-derived growth factors to the burn wound has been shown to accelerate the healing process and prevent unsatisfactory outcomes. Objective: To evaluate clinical usefulness and wound healing progress after applying Platelet Rich Plasma (PRP) to second-degree facial burn patients. Patients and Methods: We included patients with second-degree recent facial burns not exceeding 20 % of TBSA. Patients were randomly allocated to receive topical PRP application (Group A), PRP intradermal injection (Group B), and conventional facial burn care (Control group).Results: We recruited 60 patients whose ages ranged from 19 to 37 years. The time needed for complete healing for groups A, B, and the control group was 8.7, 7, and 11 days, respectively. Group A and B showed the best satisfaction rate (90% and 80%, respectively). Group A showed less early complications, while group B showed a less rate of late complications. Conclusion: Platelet-rich plasma, topical or intradermal injection, is a safe and effective option for wound healing in second-degree facial burn patients.