Silicon-mediated Transformations of Functional Groups

Abstract

"In the first work to comprehensively cover this topic, Helmut Vorbruggen provides both organic and bioorganic chemists with much new and valuable information for preparative synthesis." "Although every organic chemist may be familiar with different aspects of silylation for the protection of functional groups, this book covers the concept of protection while simultaneously silylating-activating various functional groups, such as amides and ureas. This novel methodology opens thus numerous synthetic pathways while effecting the elimination of water in it volatile persilylated form under rather mild reaction conditions, which are often advantageous compared to conventional methods."--BOOK JACKET.