Abstract
Stable isotopes enable the tracing of atoms from precursors to products via metabolic transformations in situ and in crude extracts. NMR has some unique capabilities that are especially suited for metabolic analysis, including atom position-resolved isotope analysis and isotope editing. In this chapter we describe NMR-based analysis of positional isotopomer distribution using metabolic tracers.
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Lin, P., Lane, A. N., & Fan, T. W. M. (2019). Stable Isotope-Resolved Metabolomics by NMR. In Methods in Molecular Biology (Vol. 2037, pp. 151–168). Humana Press Inc. https://doi.org/10.1007/978-1-4939-9690-2_9
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