Although there are several reports in the literature of SARS-CoV-2 infection in cats, few SARS-CoV-2 sequences from infected cats have been published. In this study, SARS-CoV-2 infection was evaluated in two cats by clinical observation, molecular biology (qPCR and NGS), and serology (microsphere immunoassay and seroneutralization). Following the observation of symptomatic SARS-CoV-2 infection in two cats, infection status was confirmed by RT-qPCR and, in one cat, serological analysis for antibodies against N-protein and S-protein, as well as neutralizing antibodies. Comparative analysis of five SARS-CoV-2 sequence fragments obtained from one of the cats showed that this infection was not with one of the three recently emerged variants of SARS-CoV-2. This study provides additional information on the clinical, molecular, and serological aspects of SARS-CoV-2 infection in cats.
CITATION STYLE
Fritz, M., Nesi, N., Denolly, S., Boson, B., Legros, V., Rosolen, S. G., … Leroy, E. M. (2022). Detection of SARS-CoV-2 in two cats during the second wave of the COVID-19 pandemic in France. Veterinary Medicine and Science, 8(1), 14–20. https://doi.org/10.1002/vms3.638
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