Abstract
Two new triterpenoids and two new sterols, named euphyperins A-D (1-4), including an oleanane-type triterpenoid (1), a lupane-type nortriterpenoid (2), and two cholestane-type steroids (3 and 4), along with five known compounds (5-9) were isolated from the twigs and leaves of Euphorbia hypericifolia. Euphyperin B (2) represents a rare lupane-type nortriterpenoid, and euphyperin C (3) is a novel 8,14-secocholestane-type steroid. Euphyperin A (1) exhibited moderate PTP1B inhibitory activity with an IC50 = 17.05 ± 1.12 μg/mL.
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CITATION STYLE
Zhao, J. X., Shi, S. S., Sheng, L., Li, J., & Yue, J. M. (2015). Terpenoids and steroids from Euphorbia hypericifolia. Natural Product Communications, 10(12), 2049–2052. https://doi.org/10.1177/1934578x1501001209
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