Activated soluble IL-2 receptor (sIL-2R) levels are elevated in a variety of diseases associated with T-cell activation. There are no reports of sIL-2R elevations in broncholitis obliterans organizing pneumonia/cryptogenic organizing pneumonia (BOOP/COP), although activated T cells are increased in BOOP/COP. We present a patient with BOOP/COP with an elevated concentration of soluble IL-2 receptors in both serum and bronchoalveolar lavage fluid. Concomitant resolution of the high serum sIL-2R and the roentogenographic findings after steroid treatment suggested that serum sIL-2R levels increase in response to a localized lymphocytic inflammatory reaction in the lung. © 2003 Tohoku University Medical Press.
CITATION STYLE
Matsuno, O., Okubo, F., Masutomo, K., Yoshida, F., Okubo, T., Miyazaki, E., & Kumamoto, T. (2003). Elevated concentrations of soluble IL-2 receptor in both bronchoalveolar lavage fluid and serum in a patient with BOOP. Tohoku Journal of Experimental Medicine, 201(1), 61–65. https://doi.org/10.1620/tjem.201.61
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