Antifouling self-assembled monolayers for designing of electrochemical biosensors

Abstract

Antifouling sensing interfaces can reduce or eliminate the non-specific absorption in electrochemical biosensing. Many antifouling strategies have been reported in the references. Self-assembled monolayer (SAM) is inexpensive and versatile for immobilization of biorecognition element onto the surface of transducer. In this work, we highlight the recent progress in antifouling SAMs and addresed their applications in electrochemical biosensors, including phenyl phosphates, small molecules, peptides and PEGylated conductive films.