Abstract
Lymph node (LN) metastasis is common in gastrointestinal cancer patients and serves as an important prognostic indicator. Fluorescence detection using 5-aminolevulinic acid (5-ALA) is a new approach to attain rapid evaluation of LN metastasis during surgery. Administration of excessive 5-ALA produces selective accumulation of fluorescent protoporphyrin IX (PpIX) in cancer cells. Here, we introduce recent advances in the fluorescence detection of LN metastases of gastrointestinal cancer by using 5-ALA.
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CITATION STYLE
Minamikawa, T., Harada, Y., & Takamatsu, T. (2015). Photodynamic detection of lymph node metastases in gastrointestinal cancer by using 5-aminolevulinic acid. In Fluorescence Imaging for Surgeons: Concepts and Applications (pp. 267–278). Springer International Publishing. https://doi.org/10.1007/978-3-319-15678-1_28
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