Severe antibody-mediated transfusion-related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non-transfused male blood donor

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Abstract

Transfusion-Related Acute Lung Injury (TRALI) has been associated with neutrophil reacting antibodies in transfused blood products. We report a case of life-threatening TRALI in an obstetric patient triggered by transfusion from a non-transfused male blood donor. A residual risk of TRALI exist, even in a male-only plasma setting.

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Agergaard, C. N., Haunstrup, T. M., Fjordside, A. L., Baech, J., Steffensen, R., & Nielsen, K. R. (2021). Severe antibody-mediated transfusion-related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non-transfused male blood donor. Clinical Case Reports, 9(6). https://doi.org/10.1002/ccr3.3818

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