Therapy for J wave syndromes

Abstract

Brugada Syndrome (BrS) and Early Repolarization syndrome (ERS) are most often diagnosed in young and active patients who present management challenges both related to risk stratification (covered in Chap. 8) and to pharmacologic and device-based therapies. Implantable cardiac defibrillators (ICDs) still represent the gold standard for the protection from sudden cardiac arrest (SCA), but their effect is confined to the termination of ventricular tachycardia (VT) and ventricular fibrillation (VF). On the other hand, pharmacological therapies and catheter ablation aim to prevent VT/VF episodes but have their own limitations. This chapter will review specific aspects of pharmacological therapy, lifestyle changes, ICD therapy and catheter ablation.