Distinction of high-grade intraepithelial neoplasia and tubular gastric adenocarcinoma

Abstract

When searching the literature for the definition of intraepithelial neoplasia (formerly dysplasia), we found it has been described as structural change of surface epithelium [1] and atypical mucosa limited to the epithelium [2]. The first international classification by Morson et al. [3] did not add anything significant to these criteria, leaving room for subjective interpretation. © 2005 Springer-Verlag Tokyo.