Efficient and eco-friendly preparation of 4-methyl-5-formyl-thiazole

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Abstract

4-Methyl-5-formylthiazole, an intermediate for synthesizing cefditoren pivoxil, was prepared in good yield by Pd/BaSO4 catalyzed hydrogenation of 4-methylthiazole-5-carboxylic acid chloride. Detailed reaction conditions have been studied. © 2008 by MDPI.

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Bai, N., Sha, Y., & Meng, G. (2008). Efficient and eco-friendly preparation of 4-methyl-5-formyl-thiazole. Molecules, 13(4), 943–947. https://doi.org/10.3390/molecules13040943

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