Synthesis and antiviral activity of new 4-(phenylamino)thieno[2,3-b] pyridine derivatives

Alice M.R. Bernardino; Luiz C.S. Pinheiro; Vitor Francisco Ferreira; Alexandre R. Azevedo; José W.De M. Carneiro; Thiago M.L. Souza; Izabel C.P.P. Frugulhetti

Journal ArticleOPEN ACCESS

Synthesis and antiviral activity of new 4-(phenylamino)thieno[2,3-b] pyridine derivatives

Bernardino A
Pinheiro L
Ferreira V
et al.

Heterocyclic Communications (2004) 10(6) 407-410

DOI: 10.1515/HC.2004.10.6.407

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Abstract

Several new 4-(phenylamino)thieno[2,3-6]pyridines (6a-e) were synthesized and tested against herpes simplex virus type 1 (HSV-1). For the first time one compound (6a) of this heterocyclic system showed 86% of inhibitory indicating that these compounds retain antiviral potency in comparison to the parent pirazolo-pyridine derivatives.

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Bernardino, A. M. R., Pinheiro, L. C. S., Ferreira, V. F., Azevedo, A. R., Carneiro, J. W. D. M., Souza, T. M. L., & Frugulhetti, I. C. P. P. (2004). Synthesis and antiviral activity of new 4-(phenylamino)thieno[2,3-b] pyridine derivatives. Heterocyclic Communications, 10(6), 407–410. https://doi.org/10.1515/HC.2004.10.6.407

Synthesis and antiviral activity of new 4-(phenylamino)thieno[2,3-b] pyridine derivatives

Abstract

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