Amlodipine or Lisinopril in Combination with Bendroflumethiazide in Clinic Blood Pressure Control among Hypertensive Tanzanians with Moderate to Severe Hypertension: A Comparison Study

Abstract

Recent guidelines have suggested combination therapy as initial treatment in hypertensive patients with ≥ grade 2 hypertension, aiming to achieve target blood pressure (BP) goal faster and more effectively. Both calcium channel blockers (CCBs) and angiotensin converting enzyme inhibitors (ACEIs) are in the list of first-line antihypertensives, however the choice of the combination therapy is left to the discretion of the clinician, and there are concerns that ACEIs are less effective in BP reduction among black hypertensives.