Flower of sphagneticola trilobata (L.) J.F Pruski from Aceh, Indonesia: Antioxidant and cytotoxic activity on HeLa cells

Abstract

This study evaluated antioxidant and cytotoxicity of methanol extract from flowers of Sphagneticola trilobata (L.) J.F. Pruski. Phytochemical Screening of the flowers exhibited the presence of alkaloid, flavonoid, phenol, saponin, steroid and absent of tannin. The flowers extract also showed good source of antioxidant with an IC50 value of 19.072 µg/ml which was categorized in the range of strong antioxidant activity (<150 ppm). Cytotoxic activity of the flowers against HeLa cell line was found to 331.287 (LC50) or 83% inhibition. The results might suggest/ support the flower of S,trilobata as source of natural antioxidant. However, further study about in vivo antioxidant and lethal dose of this sample are recommended.