Inhibitory activity of lignan components from the flower buds of Magnoliae fargesii on the expression of cell adhesion molecules

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Abstract

Inhibitory activity of lignans isolated from Magnoliae fargesii Cheng on cell adhesion molecules on the surface of THP-1 human monocytic cell lines were investigated. Among 16 lignan components tested, six displayed relatively potent inhibitory activity on the expression of both intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1).

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Ahn, K. S., Jung, K. Y., Kim, J. H., Oh, S. R., & Lee, H. K. (2001). Inhibitory activity of lignan components from the flower buds of Magnoliae fargesii on the expression of cell adhesion molecules. Biological and Pharmaceutical Bulletin, 24(9), 1085–1087. https://doi.org/10.1248/bpb.24.1085

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