ANAFILAXIA

Abstract

Systemic anaphilaxia is the result of the release of factors from several inflammatory cells. The most of them are due to drugs, insects stings, food, radiocontrast material, vaccines, heterologus sera, blood products, hyposensibilization and others. The diagnosis is relatively easy in most of the cases. The clinical picture may vary from skin lesions, such as urticaria to the lifethreatening alteration in cardiovascular or respiratory system. Adrenaline is the drug of choice together with cristaloid solution or colloids in order to restore the cardiovascular volume. Depending on the severity of the clinical picture antihistaminics or steroids may be used for the late phase of anaphilaxis. The optimal management of the patient in long term include the identification of the causal agent, patient and family instruction for the proper use of adrenaline in accidental exposure that otherwise may be fatal.