Background: Coxsackievirus A4 (CV-A4) is classified as human enterovirus A according to its serotype. CV-A4, an etiological agent of hand, foot, and mouth disease, affects children worldwide and can circulate in closed environments such as schools and hospitals for long periods. Findings: An outbreak of febrile illness at a nursery school in Beijing, China, was confirmed to be caused by CV-A4. Phylogenetic analysis of the complete genome of the isolated strain showed that the virus belongs to the same cluster as the predominant CV-A4 strain in China. This outbreak was controlled by effective measures. Conclusions: The early identification of the pathogen and timely intervention may be the most critical factors in controlling an outbreak caused by CV-A4 in a preschool.
CITATION STYLE
Li, J. S., Dong, X. G., Qin, M., Xie, Z. P., Gao, H. C., Yang, J. Y., … Duan, Z. J. (2015). Outbreak of febrile illness caused by coxsackievirus A4 in a nursery school in Beijing, China. Virology Journal, 12(1). https://doi.org/10.1186/s12985-015-0325-1
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