Exposure and dose: Health effect studies associated with nanometer aerosols

Abstract

The nanotechnology industry is rapidly growing with promises of substantial benefits that will have significant global economic and scientific impacts applicable to a whole host of areas from engineering and electronics to environmental remediation and medical healthcare. However, at present there is growing concern over the safety of nanomaterials with respect to occupational, consumer and environmental exposures and associated health effect. Particularly, information on nanomaterial exposure, dosimetry, risk assessment and health effect is negligible. In this paper we discussed the problems of the Exposure and Dose in the studies of the health effect related to nanoaerosols. As a general plan for the assessment of the Dose - the main cause of the effect - Nanoparticles Dosimetric Road Map is presented. The new ideas for measurement of the surface area of nanoparticle, local nanoparticle lung deposition, and nanoparticles respirators true effectiveness are proposed. © 2011 Ruzer LS.