Gene trees and species trees: The gene-duplication problem is fixed-parameter tractable

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Abstract

Gene Duplication is the problem of computing an optimal species tree for a given set of gene trees under the Gene-Duplication Model (first introduced by Goodman et al.). The problem is known to be NP-complete. We give a fixed-parameter-tractable algorithm solving the problem parameterized by the number of gene duplications necessary to rectify the gene trees with respect to the species tree.

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Stege, U. (1999). Gene trees and species trees: The gene-duplication problem is fixed-parameter tractable. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 1663, pp. 288–293). Springer Verlag. https://doi.org/10.1007/3-540-48447-7_29

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