Accuracy Tests of Serum Vitamin D and Calcium Levels in Chorioamnionitis Patients with Preterm Labor

Abstract

Objective: To compare the sensitivity and specificity of the diagnosis of chorioamnionitis in preterm labor using serum vitamin D and calcium in Dr. Mohammad Hoesin Hospital Palembang. Methods: This diagnostic test was carried out in the Obstetrics and Gynecology Department of Dr. Mohammad Hoesin Hospital Palembang from October 2018 to April 2019. Research subjects were women in preterm labor with chorioamnionitis. We collected 39 samples and 36 of them met the inclusion criteria. Results: Eighteen patients with hypovitaminosis vitamin D had chorioamnionitis with a sensitivity value of 94.74%, specificity 5, 88%, positive predictive value (PPV) 52.9% and Negative Predictive Value (NPV) 50%. Two of the 4 patients with hypocalcemia had chorioamnionitis with sensitivity of 10.53%, specificity 88. 24%, Positive Predictive Value (PPV) 50% and Negative Predictive Value (NPV) 46. 9%. Conclusions: Reliability of diagnosis accuracy of serum vitamin and calcium levels against chorioamnionitis is poor.