Efficient and practical procedures for the synthesis of bis-benzimidazoles in dry media under various reaction conditions

Abstract

Some different approaches have been developed in order to determine the most efficient preparation of bis-benzimidazoles 1a-f under solvent-free conditions. All of the selected methods are simple, avoiding heating with corrosive mineral acids. Heating of the reactants on a sand bath method appears to have higher efficiency. © 2005 Verlag der Zeitschrift für Naturforschung.