Semiautomatic segmentation of the medial temporal lobe anatomical structures

Abstract

Medial temporal lobe (MTL) is a region of the brain related with processing and declarative memory consolidation. Structural changes in this region are directly related with Alzheimer's disease and other dementias. Manual delimitation of these structures is very time consuming and error prone. Automatic methods are needed in order to solve these problems and make it available in the clinical practice. Unfortunately, automatic methods are not robust enough yet. The use of semiautomatic methods provides an intermediate solution with the advantages of automatic methods under the supervision of the expert. This paper propose two semiautomatic methods oriented to make the delineation of the MTL structures easy, robust and fast. © 2011 Springer-Verlag Berlin Heidelberg.