Transgenic rats with a high level of expression of the human major histocompatibility complex class I molecule HLA-B27 develop chronic inflammatory bowel disease (IBD) and arthritis. Assessment of the cecal microflora showed a rise in numbers of Escherichia coli and Enterococcus spp., corresponding to the presence and severity of IBD in these rats.
CITATION STYLE
Onderdonk, A. B., Richardson, J. A., Hammer, R. E., & Taurog, J. D. (1998). Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease. Infection and Immunity, 66(12), 6022–6023. https://doi.org/10.1128/iai.66.12.6022-6023.1998
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