Modern Anesthetics

Abstract

pt. I. Molecular Mechanisms of Anesthetic Action. The Site of Anesthetic Action / B.W. Urban -- Inhibitory Ligand-Gated Ion Channels as Substrates for General Anesthetic Actions / A. Zeller, R. Jurd, S. Lambert, M. Arras and B. Drexler, C. Grashoff, B. Antkowiak, and U. Rudolf -- Actions of Anesthetics on Excitatory Transmitter-Gated Channels / G. Akk, S. Mennerick and J.H. Steinbach -- Voltage-Gated Ion Channels / C. Nau -- G-Protein-Coupled Receptors / R.D. Sanders, D. Brian and M. Maze -- pt. II. Modern Inhalation Anesthetics. Inhalation Anaesthesia: From Diethyl Ether to Xenon / J.G. Bovill -- General Anesthetics and Long-Term Neurotoxicity / M. Perouansky -- Special Aspects of Pharmacokinetics of Inhalation Anesthesia / J.F.A. Hendrickx and A. De Wolf -- Inhalational Anaesthetics and Cardioprotection / N.C. Weber and W. Schlack -- Non-Immobilizing Inhalational Anesthetic-Like Compounds / M. Perouansky -- pt. III. Modern Intravenous Anesthetics -- Propofol / C. Vanlersberghe and F. Camu -- Pharmacokinetics and Pharmacodynamics of GPI 15715 or Fospropofol (Aquavan Injection) -- A Water-Soluble Propofol Prodrug / J. Fechner, H. Schwilden and J. Schüttler -- Etomidate and Other Non-Barbiturates / C. Vanlersberghe and F. Camu -- Remifentanil and Other Opioids / F.S. Servin and V. Billard -- Ketamine / B. Sinner and B.M. Graf -- Midazolam and Other Benzodiazepines / K.T. Olkkola and J. Ahonen -- pt. IV. Pharmacokinetics-Pharmacodynamics Based Administration of Anesthetics -- The Effect of Altered Physiological States on Intravenous Anesthetics / T.K. Henthorn -- Anesthetics Drug Pharmacodynamics / P. Bischoff, G. Schneider and E. Kochs -- Defining Depth of Anesthesia / S.L. Shafer and D.R. Stanski -- Target Controlled Anaesthetic Drug Dosing / H. Schwilden and J. Schüttler -- Advanced Technologies and Devices for Inhalational Anesthetic Drug Dosing / J.-U. Meyer, G. Kullik, N. Wruck, K. Kück and J. Manigel -- Hypnotic and Opioid Anesthetic Drug Interactions on the CNS, Focus on Response Surface Modeling / T.W. Bouillon.