Increased phenotypic switching in strains of Candida albicans associated with invasive infections

Abstract

This study reports of the rates of phenotypic switching in strains of Candida albicans isolated from superficial and invasive infections. Of 19 invasive strains, 68% showed switching activity, often at very high rates, compared with only 28% of 40 strains isolated from superficial sites (P = 0.004).