Abstract
The phenotype of Klebsiella pneumoniae HEL-1 indicates a plasmidic cephamycinase gene (bla(CMY-2)). Its sequence shows one open reading frame coding for a protein of 381 amino acids. CMY-2 is classified as class C β- lactamase that is closely related to the plasmidic enzymes BIL-1 and LAT-1 and the chromosomal AmpC of Citrobacter freundii. The bla(CMY-2) gene possibly was translocated onto a plasmid of C. freundii which spread to K. pneumoniae.
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CITATION STYLE
Bauernfeind, A., Stemplinger, I., Jungwirth, R., & Giamarellou, H. (1996). Characterization of the plasmidic β-lactamase CMY-2, which is responsible for cephamycin resistance. Antimicrobial Agents and Chemotherapy, 40(1), 221–224. https://doi.org/10.1128/aac.40.1.221
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