Molecular modeling: Considerations for the design of pharmaceuticals and biopharmaceuticals

Abstract

In this chapter, we provide the reader with a broad overview of the tools and techniques commonly used in the fields of molecular modeling and computer-assisted drug design (CADD) and at the same time present context with respect to the discovery, design, and development of therapeutic agents. Note is also made to some of the challenges that lie at the cutting edge of these disciplines. We highlight a number of techniques and related software programs as they apply to the development of therapeutic pharmaceutical and biopharmaceutical agents. © 2008 Humana Press, a part of Springer Sciencc+Business Media, LLC. All rights reserved.