The application of homing peptides to direct DNA and RNA lipoplexes to target cells is a rapidly evolving area of study, which may find application in corrective gene therapy for the treatment of neoplasms and other disorders of a genetic origin. Here, a step-wise account of the assembly and characterization of hepatocellular carcinoma cell-specific DNA lipoplexes and their cytotoxicity assessment in and delivery to the human hepatocellular carcinoma cell line HepG2 is given.
CITATION STYLE
Ariatti, M. (2016). Targeted delivery of peptide-tagged DNA lipoplexes to hepatocellular carcinoma cells. In Methods in Molecular Biology (Vol. 1445, pp. 109–136). Humana Press Inc. https://doi.org/10.1007/978-1-4939-3718-9_7
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