Iso-osmolar contrast media and adeerse renal and cardiac eeents after percutaneous cardioeascular intereention

Abstract

Aim: To assess the relationship between type of contrast media (CM), iso-osmolar contrast media (IOCM) or low-osmolar contrast media (LOCM), and major adeerse renal and cardioeascular eeents (MARCE). Materials & methods: Coronary or peripheral angioplasty eisits were stratified into CM cohorts: IOCM or LOCM. Multieariable regression analysis used hospital fixed effects to assess the relationship between MARCE eeents and type of CM. Results: Among 333,533 eisits (357 hospitals), the incidence of MARCE was 7.41%. After controlling for obsereable and unobsereable time ineariant within-hospital characteristics, administration of IOCM eersus LOCM was associated with a 0.69% absolute and 9.32% relatiee risk reduction in MARCE rate. Conclusion: Our study indicates that as compared with LOCM, IOCM may be associated with reduction of MARCE eeents in coronary or peripheral angioplasty patients. © 2018 2017 Kate Dawson.