Conjugation of poly(ethylene glycol) to proteins is a well known technique used to prolong half-life and reduce immunogenicity. In the case of interferon α, improving pharmacokinetics to reduce dosing frequency was the driving force in the development of two...
CITATION STYLE
Pasut, G. (2009). PEGylated α interferons: two different strategies to achieve increased efficacy. In PEGylated Protein Drugs: Basic Science and Clinical Applications (pp. 205–216). Birkhäuser Basel. https://doi.org/10.1007/978-3-7643-8679-5_12
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