Uptake of Tc-99m methylene diphosphonate in peritoneal metastases from breast cancer

Abstract

Distant spread from breast cancer commonly involves the bones, lungs, and liver. Metastatic involvement of the peritoneum is rare, in most cases detected only on computed tomography (CT) performed to evaluate clinical or biochemical disease progression. Several reports in the literature have described the uptake of bone-seeking radiopharmaceuticals by peritoneal metastases, the majority in the context of a primary osteogenic sarcoma, or ovarian cancer. We describe a 64-year-old woman with recurrent breast cancer presenting with contralateral axillary nodal metastases and peritoneal metastases, the latter showing avid uptake of Tc-99m methylene diphosphonate (MDP). © 2008 Lippincott Williams & Wilkins, Inc.