Spontaneous intralesional haemorrhage in dysembryoplastic neuroepithelial tumours: A series of five cases

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Abstract

Five patients with dysembryoplastic neuroepithelial tumour (DNT) showing extensive secondary haemorrhage, a finding not previously associated with these neoplasms, are described. The clinical presentations, neuroimaging findings, and histopathological features of these patients are reviewed. One patient, a previously asymptomatic 12 year old girl, presented with an acute intracerebral haemorrhage into a DNT. A further four young adults with histories of intractable partial and generalised seizures dating from childhood showed significant chronic haemorrhages within DNT, the MRI appearances in one patient giving a false impression of a cavernoma. Histopathology disclosed vascular abnormalities within these tumours which, together with other factors discussed, may have predisposed these tumours to haemorrhage.

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Thom, M., Gomez-Anson, B., Revesz, T., Harkness, W., O’Brien, C. J., Kett-White, R., … Scaravilli, F. (1999). Spontaneous intralesional haemorrhage in dysembryoplastic neuroepithelial tumours: A series of five cases. Journal of Neurology Neurosurgery and Psychiatry, 67(1), 97–101. https://doi.org/10.1136/jnnp.67.1.97

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